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Unicystic ameloblastoma (UA) refers to those cystic lesions that show clinical, radiographic, or gross features of a mandibular cyst, but on histologic examination. A clinicopathological study of 57 unicystic ameloblastomas has been undertaken, which represents 15% of all cases of ameloblastoma accessioned in our. 21 Jun Mandible / maxilla – Benign tumors / tumor-like conditions: ameloblastoma – unicystic variant.

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This paper illustrates a case of unicystic mural ameloblastoma of the mandible in an year-old female. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3. The UA which is diagnosed as subgroups 1 and 1.

There are focal epithelial invaginations associated with desmoplastic fibrosis Figure 7. Displacements of teeth irt 35, 34, 32, 31, 41, 42, and 43 were seen, with root resorption of 36 Figure 4. Apart from the most commonly encountered clinicopathologic models, there are few variants, whose biological profile is unknown or not elicited.

The inferior border of the mandible is intact. Introduction Ameloblastomas have been categorized into three biologic variants: The unicystic ameloblastoma UA is a less encountered variant of the ameloblastoma. Unicystic ameloblastoma of the maxilla: The diagnosis of unicystic ameloblastoma was based on clinical, radiological, histopathologic, and CT features.

We report a case of young female with a radiolucent lesion in the right posterior mandible. Case Report A year-old female patient presented with a chief complaint of swelling in the right lower jaw back region since months.

None, Conflict of Interest: A CT scan reveals expansion and perforation of the cortical plates and the extent of lesion Figure 6.

Histologically, the minimum criteria for diagnosing a lesion as UA is the demonstration of a single cystic sac lined by odontogenic ameloblastomatous epithelium often seen only in focal areas. Later the lesion was surgically excised and bone grafting was done to the patient. Table of Contents Alerts. Arch Pathol Lab Med.

The lesion also caused a displacement of the right inferior alveolar canal toward the cortical inferior border of the mandible. Treatment Right ameloblatoma and microvascular reconstruction with free fibular flap was done.

The remaining bone tissue showed normal contour and consistency without any clinical signs of lesion. Open in a separate window. This preponderance is predominantly marked for the dentigerous variant, where the unilocular to multilocular ratio is 4. The lesion was then aspirated; a thin straw color fluid was obtained from the lesion, which was sent for protein analysis.

Unicystic ameloblastoma of the mandible

Multilocular lesions such as ameloblastoma, odontogenic myxoma, and central giant cell granuloma were considered under differential diagnosis based on radiological picture.

Introduction Many benign lesions cause mandibular swellings, and these can unicydtic divided into odontogenic and nonodontogenic origin. Presently, the patient is under follow-up since 1 year without any signs of relapse and with bony restoration in the affected area [ Figure 4 ].

Incisional biopsy was advised and specimen submitted uunicystic histopathological examination. Unicystic tumors include those that have been variously referred to as mural ameloblastomas, luminal ameloblastomas, and ameloblastomas arising in dentigerous cysts DCs. Unicystic ameloblastoma of the mandible: UAs have clear preponderance for the unilocular pattern. Hence, it presents as a challenge both for its diagnosis and treatment.

Overlying skin was normal; no visible pulsations and no discharge were seen.

The mural extension into the cystic wall is the frequently seen feature, and the term mural UCA is used when the thickened lining either plexiform or follicular penetrates the adjacent capsular tissue [ 19 ]. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3. Footnotes Source of Support: Ameloblastomas have been categorized into three biologic variants: Nil Conflict of Interest: Discussion Many benign lesions cause mandibular swellings, whose origin can be, attributed to odontogenic or non-odontogenic causes.

Int J Oral Maxillofac Surg ; The specimen was sent for histopathological evaluation, which confirmed the diagnosis of UA. Robinson L, Martinez MG. This report highlights the importance of histopathologic analysis of any pathology in jaws even if it seems innocuous in clinical as well as radiological examination.

Accessed November 9th, Lau SL, Samman N. Immunohistochemical studies help us to know ameloblxstoma nature of the lesion and also to differentiate the same from other cysts of odontogenic origin. The excised specimen was also subjected to histopathological analysis, which confirmed the diagnosis uniycstic UA with mural proliferations.

Unicystic ameloblastoma of the mandible

But in our case it was associated with impacted mandibular canine, and it is a dentigerous variant. We report a case of UA in a year-old female with an unusual large multilocular tennis racket appearance on the right body of mandible and illustrate the importance and complexity of differential diagnosis with a brief review of recent literature.

Patient gave history of extraction of right mandibular second and third molars 2 years before the swelling ameloblastomaa.